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Index > Protein center > HADHB(Gene name) > Human
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  • HADHB (Gene name),
  • Trifunctional enzyme subunit beta, mitochondrial (Protein name ),  ECHB_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Related Databases
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  • Gene name:
    HADHB(MSTP029);
    Protein name:
    Trifunctional enzyme subunit beta, mitochondrial;
    Alternative:
    TP-beta;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Octamer of 4 alpha (HADHA) and 4 beta (HADHB) subunits.
    Function:
    N/A
    Subcellular Location:
    Mitochondrion
    Protein Attributes:
    Sequence length:
    474
    Sequence:
    50:
    MTILTYPFKN | LPTASKWALR | FSIRPLSCSS | QLRAAPAVQT | KTKKTLAKPN | 
    100:
    IRNVVVVDGV | RTPFLLSGTS | YKDLMPHDLA | RAALTGLLHR | TSVPKEVVDY | 
    150:
    IIFGTVIQEV | KTSNVAREAA | LGAGFSDKTP | AHTVTMACIS | ANQAMTTGVG | 
    200:
    LIASGQCDVI | VAGGVELMSD | VPIRHSRKMR | KLMLDLNKAK | SMGQRLSLIS | 
    250:
    KFRFNFLAPE | LPAVSEFSTS | ETMGHSADRL | AAAFAVSRLE | QDEYALRSHS | 
    300:
    LAKKAQDEGL | LSDVVPFKVP | GKDTVTKDNG | IRPSSLEQMA | KLKPAFIKPY | 
    350:
    GTVTAANSSF | LTDGASAMLI | MAEEKALAMG | YKPKAYLRDF | MYVSQDPKDQ | 
    400:
    LLLGPTYATP | KVLEKAGLTM | NDIDAFEFHE | AFSGQILANF | KAMDSDWFAE | 
    450:
    NYMGRKTKVG | LPPLEKFNNW | GGSLSLGHPF | GATGCRLVMA | AANRLRKEGG | 
    474:
    QYGLVAACAA | GGQGHAMIVE | AYPK
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    Pfam:
    KEGG:
    MIM:
    String:
    UniGene:
    SMR:
    Uniprot:
     
    FOR
    ELISA Kit for Human Trifunctional enzyme subunit beta, mitochondrial
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    E14272h
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    ELISA Kit for Human Trifunctional enzyme subunit beta, mitochondrial
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    E14272b
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    Packing:
    96T
    ELISA Kit for Human Trifunctional enzyme subunit beta, mitochondrial
    Cat.:
    E14272r
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    Packing:
    96T
    ELISA Kit for Human Trifunctional enzyme subunit beta, mitochondrial
    Cat.:
    E14272m
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    Packing:
    96T
    CLIA Kit for Human Trifunctional enzyme subunit beta, mitochondrial
    Cat.:
    U14272r
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Human Trifunctional enzyme subunit beta, mitochondrial
    Cat.:
    U14272h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Human Trifunctional enzyme subunit beta, mitochondrial
    Cat.:
    U14272b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Trifunctional enzyme subunit beta, mitochondrial
    Cat.:
    U14272m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Human Trifunctional enzyme subunit beta, mitochondrial
    Polyclonal Antibody for Human Trifunctional enzyme subunit beta, mitochondrial
    Cat.:
    P14272Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Trifunctional enzyme subunit beta, mitochondrial
    Cat.:
    P14272Rb-r
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Trifunctional enzyme subunit beta, mitochondrial
    Cat.:
    P14272Rb-h
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    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Human Trifunctional enzyme subunit beta, mitochondrial
    Monoclonal Antibody for Human Trifunctional enzyme subunit beta, mitochondrial
    Monoclonal Antibody for Human Trifunctional enzyme subunit beta, mitochondrial
    Monoclonal Antibody for Human Trifunctional enzyme subunit beta, mitochondrial
    Protein for Human Trifunctional enzyme subunit beta, mitochondrial
    Protein for Human Trifunctional enzyme subunit beta, mitochondrial
    Protein for Human Trifunctional enzyme subunit beta, mitochondrial
    Protein for Human Trifunctional enzyme subunit beta, mitochondrial

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    Linearity
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    References
    1. 1.
      "Structural analysis of cDNAs for subunits of human mitochondrial fatty acid beta-oxidation trifunctional protein."
      Kamijo T. , Aoyama T. , Komiyama A. , Hashimoto T.
      Biochem. Biophys. Res. Commun.199:818-825(1994) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
    2. 2.
      "Genomic and mutational analysis of the mitochondrial trifunctional protein beta-subunit (HADHB) gene in patients with trifunctional protein deficiency."
      Orii K.E. , Aoyama T. , Wakui K. , Fukushima Y. , Miyajima H. , Yamaguchi S. , Orii T. , Kondo N. , Hashimoto T.
      Hum. Mol. Genet.6:1215-1224(1997) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA];VARIANT TFP DEFICIENCY LYS-444
      tissue: Blood.
    3. 3.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
      tissue: Heart.
    4. 4.
      "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
      Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2)
      tissue: Stomach.
      tissue: Tongue.
    5. 5.
      "Generation and annotation of the DNA sequences of human chromosomes 2 and 4."
      Hillier L.W. , Graves T.A. , Fulton R.S. , Fulton L.A. , Pepin K.H. , Minx P. , Wagner-McPherson C. , Layman D. , Wylie K. , Sekhon M. , Becker M.C. , Fewell G.A. , Delehaunty K.D. , Miner T.L. , Nash W.E. , Kremitzki C. , Oddy L. , Du H. , more...
      Nature434:724-731(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    6. 6.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1);VARIANT SER-209
      tissue: Colon.
      tissue: Hypothalamus.
      tissue: Skeletal muscle.
      tissue: Urinary bladder.
    7. 7.
      "Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides."
      Gevaert K. , Goethals M. , Martens L. , Van Damme J. , Staes A. , Thomas G.R. , Vandekerckhove J.
      Nat. Biotechnol.21:566-569(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 34-52
      tissue: Platelet.
    8. 8.
      "The mitochondrial long-chain trifunctional enzyme: 2-enoyl-CoA hydratase, 3-hydroxyacyl-CoA dehydrogenase and 3-oxoacyl-CoA thiolase."
      Middleton B.
      Biochem. Soc. Trans.22:427-431(1994) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 48-63;CATALYTIC ACTIVITY
      tissue: Liver.
    9. 9.
      "Vectorial proteomics reveal targeting, phosphorylation and specific fragmentation of polymerase I and transcript release factor (PTRF) at the surface of caveolae in human adipocytes."
      Aboulaich N. , Vainonen J.P. , Stralfors P. , Vener A.V.
      Biochem. J.383:237-248(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 62-72 AND 96-111
      tissue: Adipocyte.
    10. 10.
      "Mitochondrial trifunctional protein deficiency. Catalytic heterogeneity of the mutant enzyme in two patients."
      Kamijo T. , Wanders R.J. , Saudubray J.-M. , Aoyama T. , Komiyama A. , Hashimoto T.
      J. Clin. Invest.93:1740-1747(1994) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBUNIT
    11. 11.
      "Lysine acetylation targets protein complexes and co-regulates major cellular functions."
      Choudhary C. , Kumar C. , Gnad F. , Nielsen M.L. , Rehman M. , Walther T.C. , Olsen J.V. , Mann M.
      Science325:834-840(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT LYS-72 AND LYS-188;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    12. 12.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    13. 13.
      "Human cytomegalovirus directly induces the antiviral protein viperin to enhance infectivity."
      Seo J.Y. , Yaneva R. , Hinson E.R. , Cresswell P.
      Science332:1093-1097(2011) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY;SUBCELLULAR LOCATION;INTERACTION WITH RSAD2
    14. 14.
      "Molecular characterization of mitochondrial trifunctional protein deficiency: formation of the enzyme complex is important for stabilization of both alpha- and beta-subunits."
      Ushikubo S. , Aoyama T. , Kamijo T. , Wanders R.J.A. , Rinaldo P. , Vockley J. , Hashimoto T.
      Am. J. Hum. Genet.58:979-988(1996) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS TFP DEFICIENCY HIS-61; HIS-247 AND GLY-263
    15. 15.
      "Molecular and phenotypic heterogeneity in mitochondrial trifunctional protein deficiency due to beta-subunit mutations."
      Spiekerkoetter U. , Sun B. , Khuchua Z. , Bennett M.J. , Strauss A.W.
      Hum. Mutat.21:598-607(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS TFP DEFICIENCY ASP-59; CYS-61; HIS-61; GLY-117; PRO-121; PRO-133; GLY-242; HIS-247; 259-GLY--PRO-270 DEL; GLY-263; ASP-280; ARG-294; LEU-294; SER-301 AND LYS-444
    16. 16.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT [LARGE SCALE ANALYSIS] VAL-119
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